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Registro Completo |
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Biblioteca(s): |
Embrapa Agricultura Digital. |
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Data corrente: |
06/01/2017 |
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Data da última atualização: |
09/02/2017 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
BUSS, C. E.; TIZIOTO, P. C.; OLIVEIRA, P. S. N.; MUDADU, M. de A.; CESAR, A. S. M.; VENTURA, R. V.; AFONSO, J.; LIMA, A. O. D.; COUTINHO, L. L.; TULLIO, R. R.; REGITANO, L. C. de A. |
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Afiliação: |
C. E. BUSS, UFSCar; P. C. TIZIOTO, CPPSE; P. S. N. OLIVEIRA, CPPSE; MAURICIO DE ALVARENGA MUDADU, CNPTIA; A. S. M. CESAR, Esalq/USP; R. V. VENTURA, Beef Improvement Opportunities, Guelph; J. AFONSO, UFSCar; A. O. D. LIMA, UFSCar; L. L. COUTINHO, Esalq/USP; RYMER RAMIZ TULLIO, CPPSE; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
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Título: |
Genome-wide efficient mixed-model study for meat quality in Nellore cattle. |
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Ano de publicação: |
2016 |
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Fonte/Imprenta: |
Journal of Animal Science, v. 94, p. 428-429, 2016. |
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DOI: |
10.2527/jam2016-0891 |
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Idioma: |
Inglês |
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Notas: |
Supplement 5. Na publicação: M. A. Mudadu. |
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Conteúdo: |
The quality of meat, which includes several traits such as tenderness, juiciness, and fat thickness, is essential for the beef industry. Previous genome-wide association studies (GWAS) using Bayesian methods have shown that Brazilian Nellore cattle have enough genetic variation for improvement of these traits. Thus, the aim of this study was to further identify quantitative trait loci (QTL) associated with meat-quality-related traits in Nellore beef cattle by using the univariate linear mixed model (LMM) approach implemented in the GEMMA software and compare it with our previous GWA studies performed using Bayesian approaches. A total of 387 Nelore steers comprising 34 half-sib families were genotyped using the IlluminaBovineHDBeadChip. We analyzed the association between markers and Warner-Bratzler shear force, backfat thickness, ribeye muscle area, scanning parameters lightness (L*), redness (a*), and yellowness (b*) to ascertain color characteristics of the meat, water-holding capacity, cooking loss, muscle pH, myofibrillar fragmentation index, saturated fat sum, omega-6 fatty acids sum, omega-3 fatty acids sum, and ethereal extract. These phenotypes were measured in the Longissimus dorsi muscle between the 11th and 13th ribs collected at slaughter. We identified fifty-three genomic regions that each contained at least one single nucleotide polymorphism (SNP) that showed a significant association with meat quality traits (1-Mb SNP windows). Highlighted, we found regions associated with three genes?neuronal growth regulator 1 (NEGR1, chr03: 70884613?71949611), dynamin 3, and phosphatidylinositol glycan anchor biosynthesis class C (DNM3/PIGC, chr16: 37340706?38007593)?related to lipid metabolism and obesity. Our results provide a better understanding of QTL regions associated with meat quality unexplored in our previous Bayesian approach. MenosThe quality of meat, which includes several traits such as tenderness, juiciness, and fat thickness, is essential for the beef industry. Previous genome-wide association studies (GWAS) using Bayesian methods have shown that Brazilian Nellore cattle have enough genetic variation for improvement of these traits. Thus, the aim of this study was to further identify quantitative trait loci (QTL) associated with meat-quality-related traits in Nellore beef cattle by using the univariate linear mixed model (LMM) approach implemented in the GEMMA software and compare it with our previous GWA studies performed using Bayesian approaches. A total of 387 Nelore steers comprising 34 half-sib families were genotyped using the IlluminaBovineHDBeadChip. We analyzed the association between markers and Warner-Bratzler shear force, backfat thickness, ribeye muscle area, scanning parameters lightness (L*), redness (a*), and yellowness (b*) to ascertain color characteristics of the meat, water-holding capacity, cooking loss, muscle pH, myofibrillar fragmentation index, saturated fat sum, omega-6 fatty acids sum, omega-3 fatty acids sum, and ethereal extract. These phenotypes were measured in the Longissimus dorsi muscle between the 11th and 13th ribs collected at slaughter. We identified fifty-three genomic regions that each contained at least one single nucleotide polymorphism (SNP) that showed a significant association with meat quality traits (1-Mb SNP windows). Highlighted, we found regions a... Mostrar Tudo |
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Palavras-Chave: |
Genome-wide association studies. |
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Thesagro: |
Gado de corte. |
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Thesaurus Nal: |
Beef cattle; Meat quality; Nellore; quantitative trait loci. |
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Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
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Marc: |
LEADER 02864naa a2200337 a 4500
001 2060128
005 2017-02-09
008 2016 bl uuuu u00u1 u #d
024 7 $a10.2527/jam2016-0891$2DOI
100 1 $aBUSS, C. E.
245 $aGenome-wide efficient mixed-model study for meat quality in Nellore cattle.$h[electronic resource]
260 $c2016
500 $aSupplement 5. Na publicação: M. A. Mudadu.
520 $aThe quality of meat, which includes several traits such as tenderness, juiciness, and fat thickness, is essential for the beef industry. Previous genome-wide association studies (GWAS) using Bayesian methods have shown that Brazilian Nellore cattle have enough genetic variation for improvement of these traits. Thus, the aim of this study was to further identify quantitative trait loci (QTL) associated with meat-quality-related traits in Nellore beef cattle by using the univariate linear mixed model (LMM) approach implemented in the GEMMA software and compare it with our previous GWA studies performed using Bayesian approaches. A total of 387 Nelore steers comprising 34 half-sib families were genotyped using the IlluminaBovineHDBeadChip. We analyzed the association between markers and Warner-Bratzler shear force, backfat thickness, ribeye muscle area, scanning parameters lightness (L*), redness (a*), and yellowness (b*) to ascertain color characteristics of the meat, water-holding capacity, cooking loss, muscle pH, myofibrillar fragmentation index, saturated fat sum, omega-6 fatty acids sum, omega-3 fatty acids sum, and ethereal extract. These phenotypes were measured in the Longissimus dorsi muscle between the 11th and 13th ribs collected at slaughter. We identified fifty-three genomic regions that each contained at least one single nucleotide polymorphism (SNP) that showed a significant association with meat quality traits (1-Mb SNP windows). Highlighted, we found regions associated with three genes?neuronal growth regulator 1 (NEGR1, chr03: 70884613?71949611), dynamin 3, and phosphatidylinositol glycan anchor biosynthesis class C (DNM3/PIGC, chr16: 37340706?38007593)?related to lipid metabolism and obesity. Our results provide a better understanding of QTL regions associated with meat quality unexplored in our previous Bayesian approach.
650 $aBeef cattle
650 $aMeat quality
650 $aNellore
650 $aquantitative trait loci
650 $aGado de corte
653 $aGenome-wide association studies
700 1 $aTIZIOTO, P. C.
700 1 $aOLIVEIRA, P. S. N.
700 1 $aMUDADU, M. de A.
700 1 $aCESAR, A. S. M.
700 1 $aVENTURA, R. V.
700 1 $aAFONSO, J.
700 1 $aLIMA, A. O. D.
700 1 $aCOUTINHO, L. L.
700 1 $aTULLIO, R. R.
700 1 $aREGITANO, L. C. de A.
773 $tJournal of Animal Science$gv. 94, p. 428-429, 2016.
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Registro original: |
Embrapa Agricultura Digital (CNPTIA) |
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| Registros recuperados : 73 | |
| 6. |  | SERRA, V.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; LIMA, A. O. de; GASPARIN, G.; COUTINHO, L. L.; MOURÃO, G. B.; REGITANO, L. C. de A. Análise de qualidade de RNA para estudo do perfil transcriptômico de animais extremos para eficiência alimentar da raça Nelore. In: JORNADA CIENTÍFICA - EMBRAPA SÃO CARLOS, 5., 2013, São Carlos, SP. Anais... São Carlos, SP: Embrapa Pecuária Sudeste: Embrapa Instrumentação , 2013. p. 12 (Embrapa Pecuária Sudeste. Documentos, 110). Editado por Ana Rita de Araújo nogueira, simone Cristina Méo Nicura| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 7. | | OLIVEIRA, P. S. N.; MALAGO JUNIOR, W.; TIZIOTO, P. C.; NASCIMENTO, M. L. do; MUDADU, M. de A.; REGITANO, L. C. de A. NEUROD1 gene is not associated with feed efficiency in Nellore cattle. In: INTERNATIONAL SYMPOSIUM ON ANIMAL FUNCTIONAL GENOMICS, 5., 2013, Guarujá. Abstract... Guarujá:[ s.n.], 2013. AB.28.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 9. | | DINIZ, W. J. S.; ROSA, K. O. da; TIZIOTO, P. C.; MOURÃO, G. B.; OLIVEIRA, P. S. N. de; SOUZA, M. M. de; REGITANO, L. C. de A. FABP1 and SLC2A5 expression levels affect feed efficiency-related traits. Agri Gene, v. 15, p. 1-7, e100100, mar. 2020.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 5 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 11. | | TIZIOTO, P. C.; MEIRELLES, S. L.; SOUZA, M. M. de; OLIVEIRA, P. S. N. de; SIQUEIRA, F.; ROSA, A. do N.; TULLIO, R. R. Screening for single nucleotide polymorphisms in MYOD1 gene and its association with meat tenderness in cattle. In: INTERNATIONAL CONFERENCE OF BRAZIL ASSOCIATION AND COMPUTER BIOLOGY 7.; INTERNATIONAL CONFERENCE OF THE IBEROAMERICAN SOCIETY FOR BIOINFORMATICS, 3., 2011, Florianópolis. Proceedings... Florianóplis: ABC3C: SolBio, 2011. ID 126| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Gado de Corte; Embrapa Pecuária Sudeste. |
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| 12. | | OLIVEIRA, P. S. N. de; TIZIOTO, P. C.; NORONHA, C. T.; MALAGO JUNIOR, W.; MUDADU, M. de A.; REGITANO, L. C. de A. A SNP in NEUROD1 is associated with production traits in Nelore beef cattle. In: REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 51., 2014, Barra dos Coqueiros. A produção animal frente às mudanças climáticas e tecnológicas - anais. Barra dos coqueiros: Sociedade Brasileira de Zootecnia, 2014. 1 CD-ROM.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 13. | | SOUZA, M. M.; MOKRY, F. C.; TIZIOTO, P. C.; OLIVEIRA, P. S. N.; SOMAVILLA, A.; CESAR, A. S. M.; MORÉ, D.; MOURÃO, G.; DINIZ, W. J. S.; MUDADU, M. A.; NICIURA, S. C. M.; ZERLOTINI, A.; REGITANO, L. C. Allele specific expression analysis in bovine muscle tissue. In: INTERNATIONAL CONFERENCE OF TH AB3C, 11.; BRAZILIAN SYMPOSIUM OF BIOINFORMATICS, 2015, São Paulo. Proceedings... São Paulo: USP-São Paulo, 2015.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 14. | | ROCHA, M. I. P.; SOUZA, M. M. de; ZERLOTINI NETO, A.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; LIMA, A. O. de; AFONSO, J.; COUTINHO, L. L.; REGITANO, L. C. de A.; NICIURA, S. C. M. Allele-specific gene expression in liver of Nelore cattle extremes for feed efficiency. In: INTERNATIONAL SOCIETY FOR ANIMAL GENETICS CONFERENCE, 36., 2017, Dublin. Proceedings... Dublin: University College Dublin, 2017. p. 156 - 157.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 15. | | SOUZA, M. M.; ZERLOTINI, A.; TIZIOTO, P. C.; OLIVEIRA, P. S. N.; SOMAVILLA, A. L.; MOKRY, F. B.; CESAR, A. S. M.; DINIZ, W. J. S.; MUDADU, M. A.; NICIURA, S. C. M.; COUTINHO, L. L.; REGITANO, L. C. A. Complex pattern of CAST allelic expression in bovine muscle tissue. In: ANNUAL INTERNATIONAL CONFERENCE ON INTELLIGENT SYSTEMS FOR MOLECULAR BIOLOGY, 22., 2014, Boston, USA. Program... [Boston]: International Society for Computational Biology, 2014. Não paginado. ISMB 2014. Pôster E13.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Agricultura Digital. |
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| 16. | | DINIZ, W. J. da S.; CESAR, A. S. M.; GEISTLINGER, L.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; AFONSO, J.; ROCHA, M. I. P.; LIMA, A. O. de; BUSS, C. E.; COUTINHO, L. L.; REGITANO, L. C. de A. Co-expression network analysis identifies genes associated with iron content in bovine muscle. In: WORKSHOP ON OMICS STRATEGIES APPLIED TO LIVESTOCK SCIENCE, 1., 2017, Piracicaba, SP. Proceedings... São Carlos, SP: Embrapa Pecuária Sudeste, 2017. p. 19. (Embrapa Pecuária Sudeste. Documentos, 125) Editores: Luiz Lehmann Coutinho, ESALQ/USP; Luciana Correia de Almeida Regitano, Embrapa Pecuária Sudeste; Gerson Barreto Mourão, ESALQ/USP; Aline Silva Mello Cesar, ESALQ/USP; Bárbara Silva Vignato, FZEA/USP; Mirele Daiana Poleti,...| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 17. | | DINIZ, W. J. da S.; CESAR, A. S. M.; GEISTLINGER, L.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; AFONSO, J.; ROCHA, M. I. P.; LIMA, A. O. de; BUSS, C. E.; COUTINHO, L. L.; REGITANO, L. C. de A. Co-expression network analysis identifies genes associated with meat tenderness. In: INTERNATIONAL SOCIETY FOR ANIMAL GENETICS CONFERENCE, 36., 2017, Dublin. Proceedings... Dublin: University College Dublin, 2017. p. 144.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 18. | | DINIZ, W. J. S.; MAZZONI, G.; COUTINHO; BANERJEE, P.; GEISTLINGER, L.; CESAR, A. S. M.; BERTOLINI. F.; AFONSO, J.; OLIVEIRA, P. S. N.; TIZIOTO, P. C.; KADARMIDEEN, H. N.; REGITANO, L. C. de A. Detection of Co-expressed pathway modules associated with mineral concentration and meat quality in nelore cattle. Frontiers in genetics, v. 10, n. 210, p. 1-12, 2019.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 19. | | OLIVEIRA, P. S. N. de; TIZIOTO, P. C.; OLIVEIRA, G. B.; CESAR, A. S. M.; DINIZ, W. J. da S.; LIMA, A. O. de; REECY, J. M.; COUTINHO, L. L.; REGITANO, L. C. de A. Differentially expressed miRNAs in skeletal muscle related to feed efficiency in Nellore cattle. Journal of Animal Science, v. 94, e-suppl. 5; Journal of Dairy Science, v. 99, e-suppl. 1, p. 159, jul. 2016.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 20. | | OLIVEIRA, P. S. N. DE; ANDRADE, B. G.; CARDOSO, T. F.; PASCHOAL, J. J.; JOSAHKIAN, L. A.; ALMEIDA, L. F.; MARCONDES, C. R.; MOURÃO, G. B.; COUTINHO, L. L.; REECY, J. M.; REGITANO, L. C. de A. Differentially expressed miRNAs in the stool of Bos indicus divergent for feed efficiency. Italian Journal of Animal Science, v. 22, supplement 1, 2023. p. 193-194. Congress of the Animal Science and Production Association, 25., Monopoli (BARI – ITALY), June 13–16, 2023.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| Registros recuperados : 73 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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